Preface
As in most medical specialties, haematology saw great change since this book was first published in 1998. We now have a greater understanding of the molecular biology of many diseases, malignant and non-malignant. The new knowledge has helped us develop more sensitive assays for many conditions, and taken to the clinic, with the engineering of new drugs, such as STI571 used in the treatment of chronic myeloid leukaemia, in the middle of the others. Like the first edition, the intention was to encompass all aspects of haematology but there is perhaps a greater emphasis on basic science than before. Readers note that the writing team is very similar to the first edition, which provides continuity of style.
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Table of content
1 Iron deficiency anaemia 1
2 Macrocytic anaemias 5
3 The hereditary anaemias 9
4 Polycythaemia, essential thrombocythaemia, and myelofibrosis 14
5 Chronic myeloid leukaemia 19
6 The acute leukaemias 23
7 Platelet disorders 28
8 The myelodysplastic syndromes 33
9 Multiple myeloma and related conditions 37
10 Bleeding disorders, thrombosis, and anticoagulation 43
11 Malignant lymphomas and chronic lymphocytic leukaemia 47
12 Blood and marrow stem cell transplantation 52
13 Haematological disorders at the extremes of life 57
14 Haematological emergencies 61
15 The future of haematology: the impact of molecular biology and gene therapy 65
Index 71
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