Treatment of Skin Disease: Comprehensive Therapeutic Strategies 5th Edition PDF Free Download
Every four years, as we plan the next edition of Treatment of Skin Disease, the editors ask ourselves these questions: Do we need another edition? Has enough changed in the practice of dermatology to justify all the work needed for another edition? Thanks to extraordinary advances in our specialty, the answer has always been an emphatic yes. The last four years has seen dramatic changes in the treatment of common dermatologic conditions like psoriasis and atopic dermatitis. Anti-IL-17 antibodies were only investigational four years ago, and now two, secukinumab and ixekizumab, are approved and a third antibody to the IL-17 receptor, brodalumab, has also been approved and is about to enter the market for psoriasis. Pure anti-IL-23 antibodies were only in experimental stages based on the earlier success of ustekinumab which blocks both IL-23 and IL-12. Guselkumab has now been released and tildrakizumab has completed phase III trials and will hopefully be approved in the coming months. Another anti-IL-23 antibody, risankizumab, is already in phase III trials and has very promising results in phase II, and other anti-IL-23 antibodies are already in development for psoriasis. Dupilumab, an anti-IL-4/IL-13 antibody has just been approved for moderate to severe atopic dermatitis, and crisaborole, a topical phosphodiesterase 4 inhibitor has been introduced for the treatment of mild to moderate atopic dermatitis. Tofacitinib, a janus kinase inhibitor, has shown substantial efficacy in psoriasis and atopic dermatitis, though regulators have not allowed approval for those diseases thus far
Dr. Taimour is a dedicated medical professional and passionate advocate for international medical graduates seeking to pursue their dream of becoming a doctor abroad. With a wealth of experience and firsthand knowledge of the challenges and rewards of this journey, Dr. Harrison is committed to helping aspiring physicians navigate the complex world of medical licensure exams, such as the USMLE and PLAB, and find their path to success in foreign medical practice.
Sharing Is Caring:
Manage Cookie Consent
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.