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The Heart in Systemic Autoimmune Diseases 2nd Edition PDF

The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities.

Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics.

Features of The Heart in Systemic Autoimmune Diseases 2nd Edition PDF:

  • Presents an impressive body of well ordered information on the topic of cardiovascular diseases and their relationship to autoimmune illness
  • Highlights key references
  • Summarizes the experience of a selected panel of distinguished physician-scientists who are actively involved in the field of cardiovascular disease and systemic autoimmunity

About the Authors:

Fabiola Atzeni received her degree in Medicine in 1995 from University of Cagliari and accreditation in Rheumatology in 2000. She received her Philosophy Doctorate in Experimental Immunology from University of Barcelona (2005). She is currently an Associate Professor and Senior Consultant at University of Messina. Before her current role, she was a Physician and Clinical Researcher at the Department of Rheumatology, Hospital L. Sacco, Milan.

Her clinical and research interest lies in immunotherapies in autoimmune diseases with particular focus on the investigation and management of differential response to biological therapies in rheumatoid arthritis (RA) and Spondyloarthritis (SpA), cardiovascular aspects of the different rheumatic diseases with particular emphasis on arteriosclerosis and infectious aspects.

Professor Doria received his medical degree and qualification in Rheumatology from the University of Padua. He was Council member of Italian College of Rheumatology (CRO) between 1999 and 2005 and a Council member of Italian Society of Rheumatology (SIR) from 2007 to 2010 and from 2013 up to now. He is also a member of American College of Rheumatology (ACR).

Table of Contents:

Chapter 1. Cellular Immunity: A Role for Cytokines

1. Introduction
2. Autoimmunity in Myocarditis
3. Pathogenesis: The Role of Cells and Cytokines

Chapter 2. Organ-Specific Autoimmunity Involvement in Cardiovascular Disease

1. Introduction
2. Post-Myocardial Infarction (Dressler) Syndrome
3. Post-Pericardiotomy Syndrome and Idiopathic Recurrent Acute Pericarditis
4. Rheumatic Carditis
5. Dilated Cardiomyopathy and Myocarditis
6. Idiopathic Tachy and Bradyarrhythmias
7. Systemic Arterial Hypertension

Chapter 3. Neonatal Lupus Syndromes: Pathogenesis and Clinical Features

1. Introduction
2. Epidemiology and Definition of Congenital Complete AVB
3. Etiology/Pathogenesis
4. Risk of Delivering a Child With Complete CHB
5. Clinical Manifestations
6. Treatment
7. Obstetric Management of Pregnancies at Risk of Developing CCHB
8. Prognosis
9. Other Pregnancy Outcomes in Women With Anti-Ro/SSA Antibodies
10. Anti-Ro/SSA Negative CHB

Chapter 4. Subclinical Cardiovascular Damage in Systemic Rheumatic Diseases

1. Introduction
2. Epidemiology and Role of Traditional Risk Factors
3. Subclinical Atherosclerosis
4. Cardiovascular Effects of Pharmacological Treatments

Chapter 5. Atherosclerosis and Autoimmunity

1. Introduction
2. Prevalence and Epidemiology
3. Pathogenesis
4. Clinical Manifestations
5. Diagnostic Investigations
6. Treatment

Chapter 6. Inflammasomes and Inflammatory Cytokines in Early Atherosclerosis

1. Introduction
2. Lipid Dysregulation in Autoimmunity
3. Innate Immunity and Inflammatory Signaling Mechanisms
4. Inflammasomes and IL-1β in Atherogenesis
5. β2-Glycoprotein I in Atherogenic Innate Immunity
6. Summary and Conclusions

Chapter 7. Treatment of Lipid Metabolism Disturbances in Autoimmune Diseases

1. Introduction
2. Lipid Metabolism Disturbances Relevant for Atherosclerosis and Cardiovascular Risk in Autoimmune Diseases
3. Serum Lipid Level Control in Autoimmune Diseases
4. Lipoprotein Function Modulation in Autoimmune Diseases

Chapter 8. Cardiac Imaging Techniques in Systemic Autoimmune Diseases

1. Introduction
2. Transthoracic Echocardiography
3. Transesophageal Echocardiography
4. Stress Echocardiography
5. Tissue Doppler Imaging
6. Speckle Tracking Echocardiography
7. Myocardial Contrast Echocardiography
8. Usefulness of Biomarkers of Endothelial Dysfunction
9. Carotid Ultrasonography
10. Conclusion

Chapter 9. New Cardiac Imaging Tools and Invasive Techniques in Systemic Autoimmune Diseases (Part II)

1. Introduction
2. Cardiac Magnetic Resonance Imaging
3. Computed Tomography
4. Right Heart Catheterization
5. Endomyocardial Biopsy
6. Conclusion

Chapter 10. Cardiac Diseases in Rheumatoid Arthritis

1. Introduction
2. Atherosclerotic Cardiovascular Disease in Rheumatoid Arthritis
3. Nonatherosclerotic Cardiovascular Disease
4. Conclusion

Chapter 11. Cardiac Involvement in Systemic Lupus Erythematosus

1. Introduction
2. Pericardial Involvement
3. Myocardial Involvement
4. Valvular Involvement
5. Coronary Artery Involvement
6. Conduction Tissue Involvement
7. Conclusions

Chapter 12. Cardiac Involvement in the Antiphospholipid Syndrome

1. Introduction
2. Epidemiology
3. Pathophysiology
4. Clinical Manifestations
5. Diagnostic Procedures
6. Differential Diagnosis
7. Treatment
8. Final Remarks

Chapter 13. Cardiac Involvement in Scleroderma

1. Introduction
2. Evidence for and Prognostic Impact of Clinical Cardiac Involvement
3. Prevalence of Subclinical Cardiac Involvement
4. Ischemic Heart Disease
5. Myocarditis
6. Hypertension
7. Arrhythmias
8. The Future

Chapter 14. Cardiac Involvement in Systemic Vasculitis

1. Introduction
2. Pathogenesis of Vasculitides
3. Cardiovascular Clinical Manifestations in Vasculitides
4. Evolution and Prognostic Factors
5. Treatment
6. Conclusions

Chapter 15. Cardiovascular Involvement in Ankylosing Spondylitis

1. Introduction
2. Cardiovascular Mortality in Ankylosing Spondylitis
3. Vascular Morbidity in Ankylosing Spondylitis
4. Cardiovascular Risk Factors in Ankylosing Spondylitis
5. Aortic Disease in Ankylosing Spondylitis
6. Mitral Valve Involvement in Ankylosing Spondylitis
7. Conduction Abnormalities in Ankylosing Spondylitis
8. Myocardium and Pericardium in Ankylosing Spondylitis
9. Subclinical Vascular Involvement in Ankylosing Spondylitis
10. Treatment and Its Implications in Atherosclerosis in Ankylosing Spondylitis
11. Conclusions

Chapter 16. Cardiovascular Involvement in Psoriatic Arthritis

1. Introduction
2. Epidemiology
3. Etiology/Pathogenesis
4. Clinical Manifestations
5. Diagnostic Investigations
6. Treatment

Chapter 17. Cardiovascular Involvement in Primary Sjögren’s Syndrome

1. Introduction
2. Raynaud Phenomenon
3. Cardiovascular Disease
4. Autonomic Cardiovascular Features
5. Pulmonary Arterial Hypertension
6. Arrhythmias
7. Pericarditis
8. Myocarditis

Chapter 18. Gout and Heart Disease: A Two-Way Street?

1. Introduction
2. Gout—Overview
3. Cardiovascular Disease
4. Gout and Traditional Cardiovascular Risk Factors
5. Etiology and Pathogenesis
6. Diagnostic Interventions
7. Treatment
8. Future Perspectives
9. Conclusion

Chapter 19. Heart Involvement in Osteoarthritis

1. Introduction
2. Prerequisites: Pathophysiology of Osteoarthritis
3. Epidemiologic Data: Osteoarthritis and Cardiovascular Diseases, Two Endemic Diseases
4. Association Between Osteoarthritis and Cardiovascular Diseases: Shared Risk Factors
5. Association Between Osteoarthritis and Cardiovascular Diseases: Direct Link Beyond CV Risk Factors
6. Association Between Osteoarthritis and Cardiovascular Diseases: an Epiphenomenon?
7. New Perspectives: The Role of Microbiota
8. Conclusions

Chapter 20. Cardiac Effects of Antirheumatic Drugs

1. Introduction
2. Atherosclerosis and Metabolic Syndrome
3. Other Heart Diseases
4. Recommendations for Cardiovascular Risk Management in Arthritides
5. Conclusions.

Product Details:

  • Series: Handbook of Systemic Autoimmune Diseases (Book 14)
  • Hardcover: 566 pages
  • Publisher: Elsevier Science; 2 edition (March 18, 2017)
  • Language: English
  • ISBN-10: 9780128039977
  • ISBN-13: 978-0128039977
  • ASIN: 0128039973
  • Product Dimensions: 6 x 1.2 x 9 inches
  • Shipping Weight: 2.3 pounds.

Cardiological Society of India Cardiology Update 2019 PDF

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