Cellular and Molecular Immunology 8th Edition PDF Free Download
This eighth edition of Cellular and Molecular Immunology includes substantial additions and revisions, which we made to keep the textbook current with scientific advances and, at the same time, maintain the clear and readable style that has been typical of past editions. Whenever we have added new information, we have focused primarily on important concepts and have not increased the length of the book. We have also rewritten many sections for increased clarity, accuracy, and completeness. Among the major changes is a reorganization of the chapters dealing with T lymphocyte responses in order to more clearly describe early T cell activation events, differentiation and functions of subsets of CD4+ helper T cells, and functions of CD8+ cytotoxic T cells. In addition, the entire book has been updated to include important recent advances in immunology. Some of the topics that have been significantly revised are innate lymphoid cells, the developmental pathways of macrophages and dendritic cells, and immune checkpoints in tumor immunity. It is remarkable and fascinating to us that new principles continue to emerge from analyses of the complex systems that underlie immune responses. Perhaps one of the most satisfying developments for students of human disease is that basic principles of immunology are now laying the foundation for rational development of new immunologic therapies. Throughout the book, we have tried to emphasize these new therapeutics and the fundamental concepts on which they are based. We have also continued to improve our illustration program. New figures have been added, and previously used figures have been reviewed and often changed for accuracy and clarity. We have kept design features such as the use of bold italic text to highlight “take-home messages” to make the book easy to read. The lists of suggested readings continue to emphasize recent review articles that provide in-depth coverage of particular topics for the interested reader. We have divided the lists into sections based on themes to help readers find the most useful articles for their needs.
Cellular and Molecular Immunology 9th Edition PDF Free Download
This ninth edition of Cellular and Molecular Immunology includes substantial revisions, which we made to keep the textbook current with scientific advances and, at the same time, maintain the clear and readable style that has been typical of previous editions. Whenever we have added new information, we have focused primarily on important concepts and have not increased the length of the book. We have also rewritten many sections for increased clarity, accuracy, and completeness. A general theme in modern immunology is that the field is moving beyond establishing fundamental principles of the mechanisms of immune responses to applying these principles to understand human disease and develop new therapies. The revolution in immunological therapies over the last twenty years has been extraordinary. It is especially satisfying for immunologists that some of the most innovative and effective immunotherapies have been developed because the basic science has matured and the complex mechanisms of immune activation and regulation have been elucidated in increasing detail. In this edition of the book, we have paid special attention to the clinical relevance of immunology and have emphasized how newly developed therapies work and what their strengths and pitfalls are. In addition to these translational aspects of immunology, we have also updated basic concepts wherever there has been significant new understanding. Some examples of these fundamental advances include current views on innate lymphoid cells, the biology of inflammasome activation, the role of follicular helper T cells in antibody responses in germinal centers, newly described memory lymphocyte subsets, and the protective and pathogenic roles of effector T cells.
In this post we have shared an overview and download link of THE IMMUNOASSAY HANDBOOK 4TH EDITION PDF. Read the quick review below and download the PDF by using links given at the end of the post.
The fourth edition of The Immunoassay Handbook provides an excellent, thoroughly updated guide to the science, technology and applications of ELISA and other immunoassays, including a wealth of practical advice. It encompasses a wide range of methods and gives an insight into the latest developments and applications in clinical and veterinary practice and in pharmaceutical and life science research.
Highly illustrated and clearly written, this award-winning reference work provides an excellent guide to this fast-growing field. Revised and extensively updated, with over 30% new material and 77 chapters, it reveals the underlying common principles and simplifies an abundance of innovation.
Features of PDF:
Following are the faetures of this book given below;
The Immunoassay Handbook reviews a wide range of topics, now including lateral flow, microsphere multiplex assays, immunohistochemistry, practical ELISA development, assay interferences, pharmaceutical applications, qualitative immunoassays, antibody detection and lab-on-a-chip.
This handbook is a must-read for all who use immunoassay as a tool, including clinicians, clinical and veterinary chemists, biochemists, food technologists, environmental scientists, and students and researchers in medicine, immunology and proteomics.
It is an essential reference for the immunoassay industry.
Provides an excellent revised guide to this commercially highly successful technology in diagnostics and research, from consumer home pregnancy kits to AIDS testing. www.immunoassayhandbook.com is a great resource that we put a lot of effort into.
The content is designed to encourage purchases of single chapters or the entire book.
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Well-written, readable, and superbly illustrated, Cellular and Molecular Immunology, 10th Edition, continues the tradition of excellence established through multiple editions of this bestselling text. Offering an unparalleled introduction to this complex field, it retains a practical, clinical focus while updating and revising all content to ensure clarity and comprehension.
This book bringing readers fully up to date with new and emerging information in this challenging area. It’s an ideal resource for medical, graduate, and undergraduate students, as well as a trusted reference for physicians and scientists.
Highlights the implications of immunologic science for the management of human disease, emphasizing clinical relevance throughout.
Employs a highly accessible writing style that makes difficult concepts easier to understand, and provides clear implications of immunologic science to the management of human disease and clinical practice.
Features updates from cover to cover, including new information on intracellular sensors of innate immunity, therapeutic use of monoclonal antibodies, regulation of migration events during T cell-B cell interactions, regulatory and transcriptional events in germinal center formation, immunology of infectious diseases including coronaviruses, human immunodeficiency disorders, and immunology of HIV.
Provides a highly visual, full-color description of the key immunologic and molecular processes with a fully updated, comprehensive, and consistent art program, including many new and extensively revised illustrations.
Helps readers grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions.
Includes summary boxes that assist with rapid review and mastery of key material.
Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California.
You can easily download free by clicking the link given below.
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Meticulously reviewed and updated for today’s medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology.
This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases―all designed to help students master this complex topic in the most efficient, effective manner possible.
Emphasizes clinical aspects of immunology, including disease pathogenesis, the development of novel therapies based on basic science, and an appendix of clinical cases for real-world application.
Provides top-notch instruction from experienced teachers, course directors, and lecturers led by well-known editor and author Dr. Abul Abbas.
Features a highly readable writing style and practical organization, now with fully revised content and updated images to reflect recent important advances in today’s understanding of the immune system.
Provides additional online features such as answers to in-book chapter review questions, helpful animations, and up to 10 self-assessment questions per chapter.
Presents information in a format and style that maximizes usefulness to students and teachers studying medicine, allied health fields, and biology.
Contains numerous features designed to help students understand key immunologic concepts: high-quality illustrations, practical tables, chapter outlines, bolded key points, and focus questions in every chapter for self-assessment and review.
Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California
You can easily download free by clicking the link given below.
“ NOTE: We do not own copyrights to these books. We’re sharing this material with our audience ONLY for educational purpose. We highly encourage our visitors to purchase original books from the respected publishers. If someone with copyrights wants us to remove this content, please contact us.“
Skin is the largest and most superficial organ of the body. It serves as a protective boundary against the environment and hosts numerous immune system cells. The skin also functions as a sensory organ, providing information about environmental stimuli such as heat, cold, pain, and touch. Immunology of the skin is an important topic because it involves understanding how the immune system responds to different insults, such as UV radiation, chemicals, and physical injuries.
Features of Immunology of the Skin PDF
Skin is an organ of the body that has a protective function against the environment. It is made up of three layers: the epidermis, dermis, and subcutaneous layer. The epidermis is the outermost layer and is made up of squamous cells. The dermis is the middle layer and contains collagen and other fibrous proteins. The subcutaneous layer is underneath the dermis and consists of fat and connective tissue. Immunology is the study of how the body’s immune system responds to different substances or organisms. There are two types of immunity: innate immunity and adaptive immunity. Innate immunity is present from birth and depends on your genetics. Adaptive immunity develops after you encounter a substance or organism for the first time. It depends on your immune genes, which are acquired from your parents or from other people in your life.
The skin is the largest organ of the body and it plays an important role in protecting us from the environment. The skin contains several cells subsets, each of which plays a specific role in defending against infection. This book reviews the role of each cell subset in the skin, providing the basics for understanding skin immunology and the . In the past 10 years, knowledge of immunology has expanded drastically in areas such as innate immunity (Toll-like receptors, C-type lectins), and host defenses to bacteria and viruses, and this increased knowledge has led to the development of more effective treatment of psoriasis and other skin diseases. This book provides updates on the mechanisms of skin diseases including contact dermatitis, atopic dermatitis, psoriasis, urticaria, drug eruption, bullous diseases, anaphylaxis, graft-versus-host disease, rosacea, lymphoma, photodermatology, and collagen vascular diseases. Understanding the basics of skin immunology will help clinicians and dermatologists use new therapeutics such as biologics efficiently. Serving as an intermediary between basic science and clinical medicine, this book gives readers the opportunity to understand and marvel at the mystery and fascination of skin immunology.
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Description of Immunology of the Skin PDF
Immunology of the Skin PDF is one of the best-known books for Dermatologists. This book covers all the cases and phenomenons a student and professional doctor might be up against in their whole life. Master this book and you will be of prime help in solving cases of diseases that are difficult to treat. Make a difference. Download Now.
The Authors
Michael Reid, MSN, RN, CCRN has been in critical care since entering the field of nursing many years ago. Initially being exposed to a cardiovascular surgical intensive care unit, Michael went on to work in medical, surgical, and trauma specialized intensive care units. Michael oversees the development of educational products for his company, Nursology / The NCLEX Cure, and as a consultant for companies and corporations. He is currently dividing his time between working in the ICU, teaching NCLEX and CCRN, writing books, and building new and exciting methods for education in nursing.
Dimensions and Characteristics of Immunology of the Skin PDF
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Compared with the book of which title was shared decades ago, I found a number of distinctive issues presented in this current book. For instance, in terms of anatomy, the previous concerns were about the facial nerve and the sensory nerve. It has shifted and highlighted on the vascular network. In case of operation/ procedure which used to focus only the facial surgery procedure (eg. facelift ) to both of the surgical and the non-surgical facial rejuvenation. This point includes filler and botulinum toxin injection. These have been received a lot of attention currently. The authors also step forward to the energy device issues and so forth. They are generous enough to share their valuable and meticulous experiences which cannot be found elsewhere.
On top of that, the main contributors are the world-leading and world authority plastic surgeon who has been widely recognized across the world. They are also a highly proficient person with expertise not only in the surgery but also in the non-surgical aesthetic procedures. According to this book, the authors evidentially demonstrates the high academic standard.
What I am impressed a great deal with this book are their fascinating illustrations, VDO, and cadaveric dissection. Those pictures are not only that beauty but also revealing a smart presentation method. These enable us to understand the content, particularly on focusing on the plane of various structures.
The book is worth buying.”
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Viruses are studied either because they cause significant human, animal or plant disease or because they are useful materials for probing basic phenomena in biology, chemistry, genetics and/or molecular biology. Arenaviruses are unusually interesting in that they occupy both categories. Arenaviruses cause several human diseases known primarily as the hemorrhagic fevers occurring in South and Latin America (Bolivia: Machupo, Argentine, Junin virus, and Brazil: Sabia virus) and in Africa (Lassa fever virus). Because such viruses produce profound disabilities and often kill the persons they infect, they are a source of health concern and economic hardship in the countries where they are prevalent. Further, they provide new problems for healthcare persons owing to the narrowing of the world as visitors from many countries travel increasingly to and from endemic areas and may incubate the infectious agent taking it from an endemic area into an area where the virus is not expected. Such cases are now being recorded with increasing frequency. In addition to these hemorrhagic fever viruses, the arenavirus lymphocytic choriomeningitis virus (LCMV) can infect humans worldwide,although the illness is most often less disabling and severe than those elicited by the other arenaviruses. Yet, LCMV is of greater concern to non-arenavirologists and experimentalists using tissue culture or animals, etc., because normal-appearing cultured cells or tissues from animals used for research may be persistently infected with LCMV without manifesting clinical disease or cytopathology and may transmit that infection to laboratory workers·. For example, in 1975 Heinemann et aI., recorded 48 cases of LCMV infection among personnel in the Radiotherapy Department and vivarium at the University of Rochester School of Medicine. These persons had contact with Syrian hamsters into which tumors, unknown to be infected with LCMV, were injected. The tumor cells were obtained from an outside, well-known, research supplier who distributed tumor cell lines to numerous laboratories primarily interested in SV40 and polyoma virus research. A subsequent investigation of the 22 tumor lines revealed that 19 yielded in fectious LCMV. Thus, both production of SV 40 and/or polyoma virus from these cells or the use of hamsters infected with such tumors provided an unanticipated human biohazard. In the Rochester scenario infection was spread from those doing basic research, presumably via air ducts to multiple individuals at the medical school/hospital including healthcare workers and patients undergoing radiologic procedures. Similarly, the Centers for Disease Control (CDC), USA, has recorded multiple cases of LCMV infection in families scattered from the northeast coast of the United States (New York) to the western region (Reno, Nevada) originating from hamsters sold by a single pet store supplier in the southeast (Florida). In addition, several investigators found that their hybridomas making monoclonal antibodies were infected with LCMV. The likely source was infected spleen feeder layers from clinically healthy but persistently infected mice purchased from a well-known commercial source which supplies mice to many universities and institutes in North America. Thus, researchers studying such diverse areas as the molecular biology of SV 40, biological effects of Chlamydia, immune response of mice, and producing hybridoma cells or ascites fluids have found their preparations contaminated with LCMV. In these cases, the potentially dangerous effects of LCMV were not anticipated because the virus does not cause footprints associated with most acute viruses (i.e., n~crosis, inflammatory response). The recognized arenaviruses of man, vectors and laboratory models used for their study are listed in Table 1.
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The Atlas of Immunology is designed to provide a pictorial reference and serve as a primary resource for the most up-to-date and thorough illustrated treatise available in the complex science of immunology. The book contains more than 1,000 illustrations and depicts essentially every concept of importance in understanding the subject matter of immunology. It is addressed to immunologists and nonimmunologists alike, including students, researchers, practitioners, and basic biomedical scientists. Use of the book does not require prior expertise. Some of the diagrams illustrate basic concepts, whereas others are designed for the specialist interested in a more detailed treatment of the subject matter of immunology. The group of illustrations is relatively complete and eliminates the need to refer to another source. The subject matter ranges from photographs of historical figures to molecular structures of recently characterized cytokines, the major histocompatibility complex molecules, immunoglobulins, and molecules of related interest to immunologists.
The subject matter is divided into chapters that follow an outline that correlates with a standard immunology textbook. This provides for a logical and sequential presentation and gives the reader ready access to each part of the subject matter as it relates to the other parts of the publication. These descriptive illustrations give the reader a concise and thorough understanding of basic immunological concepts that often intersect the purview of other basic and clinical scientific disciplines. A host of new illustrations, such as cellular adhesions molecules, is presented in a manner that facilitates better understanding of their role in intercellular and immune reactions. Figures that are pertinent to all of the immunological subspecialties, such as transplantation, autoimmunity, immunophysiology, immunopathology, antigen presentation, the T-cell receptor, to name a few, may be found in this publication. Those individuals with a need for ready access to a visual image of immunological information will want this book to be readily available in their bookshelf. No other publication provides the breadth or detail of illustrated immunological concepts as may be found in the Atlas of Immunology.
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In any movement of their life, immune cells, especially T and B lymphocytes, are confronted with an essential choice: to continue their existence or to commit a sort of metabolic suicide that is referred to as apoptosis or programmed cell death. In contrast to most philosophers, lymphocytes and their precursors are constantly susceptible to suicide, and it even appears that the usual cause of T or B cell elimination is suicide rather than death from natural causes, accidents or murder. This book provides a vast overview of lymphocytes suicide: external triggers and internal motives leading to suicidal impulses, accomplices in self-destruction, weapons implicated in self-execution, removal of dead bodies and pharmacological prevention of suicide.
Most of the chapters in this book are devoted to the physiology of apoptosis. The goal is to unmask the external triggers of apoptosis, unravel the signal transduction processes involved therein and describe the role of oncogenes, “death genes” and effector molecules in the apoptotic cascade. The remaining chapters deal with the pathophysiological aspects of lymphocyte apoptosis, namely, as a host contribution to HIV-induced lymphopenia, and therapeutic strategies for the avoidance of lymphocyte death.
We are confident that this compendium will contribute to the exploration of cellular suicide, not only from a basic scientist’s viewpoint but also with regard to the possible clinical implications of apoptosis (dys)regulation. Far from having a depressing effect on the reader, cellular suicide may thus provide a source of both intellectual excitement and therapeutic inspiration.
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Antigen presentation is a subject most often considered at the molecular level, but its results are, of course, also relevant to the whole organism. This compilation of chapters from experts is aimed at reviewing the broad spectrum from molecular, biochemical and pharmacological considerations through to the effects on host immunity and the diseases which result from defects in these pathways. We begin with the class I MHC pathway. Drs. Nandi, Marusina and Monaco review how the endogenous peptides are generated within the cell and how they are transported into the endoplasmic reticulum. There, the story is taken up by Drs. Fourie and Yang, who relate how the complexes are assembled and transported to the cell membrane. Drs. Hudrisier and Gairin then describe the structure ofthe mature class I complex and reflect upon the pharmacology and possible therapeutic use of peptide antagonists. The following two chapters illustrate the consequences of low class I MHC expression. The defects in immune responsiveness which result from globally defective class I presentation are reviewed by Drs. Frelinger and Serody, who describe the resultant defects in the ability to control challenge by different microbial pathogens, while Dr. RaIl argues that the restricted class I expression, seen in certain tissues of normal animals, is most probably beneficial to the host, preventing immunopathologically mediated cell death. Then, the interface between the host and several viral pathogens is addressed in Chaps. 7 and 8; Drs. Sparer and Gooding describe how adenoviruses interfere with antigen presentation and, thus, with the host’s ability to respond appropriately to the virus challenge. Drs. Johnson and Hill show how, even in a single virus family (the herpes viruses), many different approaches to immune evasion have been taken. In Chap. 9, Drs. Nordeng, Gorvel and Bakke provide an excellent review of the MHC class II pathway, demonstrating that the invariant chain has many and varied functions. In the final chapter, Drs. Eibl and Wolff discuss the consequences of a defective MHC class II pathway in transgenic mouse models and in humans.
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