The first edition of Netter’s Cardiology was an effort to present to clinicians the ever-increasing amount of medical information on cardiovascular diseases in a concise and highly visual format. The challenge that clinicians face in “keeping up” with the medical literature has continued to grow in the 5 years since the first edition of Netter’s Cardiology. This need to process the everexpanding medical information base and apply new findings to the optimal care of patients is acute in all areas of medicine, but perhaps it is most challenging in disciplines that require practitioners to understand a broad spectrum of evidence-based medicine, such as the field of cardiovascular diseases. The explosion of medical knowledge is also a very real educational issue for learners at all levels—students, residents, practicing physicians— who must rapidly determine what is and is not important, organize the key information, and then apply these principles effectively in clinical settings. For the second edition of Netter’s Cardiology, our goal was to produce an improved text that keeps these issues in clear focus and also addresses important clinical areas that were not well covered in the first edition or in many other cardiology texts. To accomplish this expansion while maintaining a concise text that could be used as a ready reference, we again avoided exhaustive treatment of topics. We also have made every effort to present the essential information in a readerfriendly format that increases the reader’s ability to learn the key facts without getting lost in details that can obfuscate the learning process. After a careful review of reader comments about the first edition, we made some substantial changes to achieve our educational goals. Chapters were added and topics expanded to address reader concerns about the lack of coverage of a number of important topics commonly encountered in clinical practice. Examples include these new chapters: Chest Radiography, Echocardiography, Stress Testing and Nuclear Imaging, Cardiac Computed Tomography and Magnetic Resonance Imaging, Left and Right Heart Catheterization, Identifying the Patient at High Risk for Acute Coronary Syndrome: Plaque Rupture and “Immediate Risk,” Cardiogenic Shock after Myocardial Infarction, Stress-Induced Cardiomyopathy, Supraventricular Tachycardia, Sleep Disorders and the Cardiovascular System, Cardiovascular Toxicity of Noncardiac Medications, and Sudden Cardiac Death in Athletes. The chapter subheadings of “Optimum Treatment” and “Avoiding Treatment Errors” are new additions that address concerns about therapeutic errors that can lead to patient harm.